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Becker's nevus

Common, acquired benign pigmentary hamartoma. Epidemiology: 1) teenage boys 2) incidence 0.52% males 17-26 years of age 3) onset: a) 50% before age 10 b) 25% age 10-15 c) 25% after age 15 4) male/female ratio 5:1 Pathology: 1) benign nevoid hypermelanosis [2] 2) acanthosis, regular with some hyperkeratosis 3) occasional horn cysts 4) no nevomelanocytes present 5) melanocytes in normal numbers 6) basal layer keratinocytes packed with melanin Genetics: familial cases reported Clinical manifestations: 1) unilateral patchy brown hyperpigmentation 2) generally occurs on shoulders 3) lesions 1st appear at puberty a) hair generally not present at the onset of hyperpigmentation b) terminal hair (dark & coarse) generally appears within 1 year c) hypertrichosis frequently develops several years later [2] d) increased hair growth localized to hyperpigmented areas 4) large, singular plaque a) mean size 125 cm2 b) jagged edges 5) light tan or brown; not uniform color 6) barely palpable 7) distribution: a) shoulder & submammary area 32% b) lower back 23% c) upper back 19% d) submammary 13% e) arms 3% f) legs 3% * images [3] Laboratory: skin biopsy if indicated Differential diagnosis: 1) giant congenital melanocytic nevus a) present at birth b) distinctly elevated 2) Albright's disease a) congenital b) no hair c) pigmentation uniform Management: -> prognosis: a) pigmentation extends for 1-2 years, then remains stable b) fading is rare c) benign lesion; cosmetic concern only

General

nevus hamartoma

References

  1. Color Atlas & Synopsis of Clinical Dermatology, Common & Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 302
  2. Sadlier M, O'Regan GM Becker's Nevus. N Engl J Med 2015; 372:1249. March 26, 2015 PMID: 25806917 http://www.nejm.org/doi/full/10.1056/NEJMicm1402443
  3. DermNet NZ. Becker naevus (images) http://www.dermnetnz.org/lesions/beckers-naevus.html